ACUTE TOXICITY TEST
Mr. Lui & Ms. Chan
“Y” fomula, supplied by Guangdong Star Medicine Science and Technology Development Company.
NIH breed mice supplied by Guangdong Provincial Experiment Animal Farm.
Experiment Procedure and Result :
A. Medicine Treatment: Condense 1,000 ml. of “Y” Formula Into 100 ml. over double boiler to be used In the experiment. B. Acute Toxicity test through oral administration on mouse: select 30 mice weight between 20 to 22g. 15 MALE AND 15 FEMALE. Feed mice with the entire dosage condensed Formula – (equivalent to the strength of 70.61 ml/kg. of the original medicine). Observe mice for 7 days after feeding. All mice survived with a normal appetite. It is observed that the mice can take up to 70.61 ml./kg. of “Y” Formula orally without any problem. (For an average adult of 50 kg. in China, normal dosage is 30 ml. per day orally.) The dosage in this test is equivalent to117 times of the normal dosage. The dosage of 20 ml. per day per adult is recommended for clinical testing.